Theralymph First General Annual Meeting
We were honored to introduce our consortium: Dr Kari Alitalo (Finland), Dr Tatiana Petrova (Switzerland), Dr Miikka Vikkula (Belgium), Dr Agnès Noël (Belgium), Dr Lenka Romeislova (Czeck Republic), Dr Gilles Pagès (France), Dr Taija Makinen (Sweden), Flash Therapeutics (France), the Clinical Investigation Center of Toulouse (France) and Inserm Tranfert.
Introduction : Lymphedema is a disorder of the lymphatic vascular system characterized by impaired lymphatic return and swelling of the extremities and accumulation of undrained interstitial fluid/lymph that results in fibrosis and adipose tissue deposition in the affected area. It can be an inherited condition (primary lymphedema) or occurs after cancer surgery and lymph node removal (secondary lymphedema). It causes a significant morbidity and is a common disabling disease affecting more than 120 million people worldwide, however there is no curative treatment for lymphedema. Therefore, our main objective will be to establish a multiple gene therapy for lymphedema. We will focus on women who developed secondary lymphedema after breast cancer. This meeting will consist in presenting the work teams as well as the distribution of each work packages in Theralymph project.
Hourly Schedule
Theralymph First General Annual Meeting
- 13:00 -
- Welcome and overview of the meeting
- Barbara Garmy-Susini
- 13:00 - 13:15
- WP Objectives, achievements first 12 months and plans for the next 6 months
- Christiane Dascher-Nadel (IT, Marseille France)
- 13:15 - 13:20
- WP Objectives, achievements first 12 months and plans for the next 6 months
- Barbara Garmy Susini, Inserm
- 13:20 - 13:40
- WP1 Pathophysiology of lymphedema: risk factor associated with lymphedema - PARTNER PRESENTATIONS
- Gilles Pages laboratory (CNRS) Barbara Garmy Susini laboratory (Inserm)
- 13:40 - 13:50
- Discussion
- 13:50 - 14:20
- WP2 Architecture of the collecting vessels in the adipose tissue - PARTNER PRESENTATIONS
- Taija Mâkinen laboratory (UU) Barbara Garmy Susini laboratory (Inserm) Kari Alitalo (UnivHel) Miika Vikkula (DDUV)
- 14:20 - 14:35
- Discussion
- 14:35 - 14:55
- WP3 Adipocyte dysfunction in lymphedema - PARTNER PRESENTATIONS
- Barbara Garmy Susini (Inserm) Lenka Rossmeislova (CUNI)
- 14:55 - 15:05
- Discussion
- 15:05 - 15:25
- WP4 Resolution of inflammation in lymphedema - PARTNER PRESENTATIONS
- Tatiana Petrova (UNIL) Barbara Garmy Susini (Inserm)
- 15:25 - 15:35
- Discussion
- 15:35 - 16:45
- COFFEE BREAK
- 15:45 - 16:15
- WP5 Validation of therapeutic targets in vitro - PARTNER PRESENTATIONS
- Agnes Noël (ULIEGE) Barbara Garmy Susini (Inserm) Kari Alitalo (UnivHel) Tatiana Petrova (UNIL)
- 16:15 - 16:30
- Discussion
- 16:30 - 17:00
- WP6 Validation of therapeutic targets in vivo in mice model of lymhedema - PARTNER PRESENTATIONS
- Barbara Garmy Susini (Inserm) Regis Gayon (FTX) Kari Alitalo (UnivHel) Agnes Noël (ULIEGE)
- 17:00 - 17:15
- Discussion
- 17:15 - 17:30
- GENERAL CONCLUSION
- 17:30 -
- End of Meeting